眾所周知頭頸部癌症可能是致命的,即使採用最先進的治療方法,也往往會有很高的複發率。

美國癌症協會估計,2015年將診斷出大約13,560例喉癌新病例,其中大多數病例發生在男性身上。今年將有大約3,640人死於喉癌。預計2015年將診斷出超過15,000例新的咽喉癌(咽喉癌)病例,大多數病例均在男性中被診斷出來。


大多數喉癌始於聲帶位於頸部的部分。其餘大部分開始於聲帶上方區域,其餘部分位於聲帶下方。幸運的是,喉癌發病率穩步下降,每年2%至3%。這被認為是由於較低的吸煙率,這是頭頸部癌症的主要危險因素。



頭頸部癌症難以根除的一個原因是它們抑制了身體對異常細胞的免疫反應。這使得癌細胞更容易抵抗身體的免疫系統。但是,一項新的研究發現了一種可能的治療方法:勃起功能障礙藥物他達拉非(Tadalafil)是犀利士的活性成分。



他達拉非(Tadalafil)(犀利士)和治療喉癌


邁阿密米勒醫學院的研究人員最近宣布,他達拉非(Tadalafil)可能對某些類型的咽喉癌具有抗腫瘤作用。邁阿密先驅報採訪了一位62歲的患者,該患者在喉癌復發後參與了臨床試驗。共有35名患者參與,醫生們發現“中等”劑量的他達拉非(Tadalafil)以這樣的方式影響患者的免疫系統,這表明它可以抑制癌細胞的生長。


與“邁阿密先驅報”採訪的患者Mark Giattini說,在進行最近一次手術之前,由於腫瘤在那里長大,他的喉嚨疼痛嚴重。在服用他達拉非(Tadalafil)之前,由於疼痛,他幾乎無法進食。然而,在服用該藥僅10天后,他說疼痛明顯消退。

犀利士官網:https://www.cialiusa.tw/

儘管在Giattini手術的外科醫生Donald Weed醫生表示腫瘤沒有縮小那麼多,但他認為他達拉非(Tadalafil)可能增強了抵抗感染的免疫細胞,抑制了疾病的傳播。服用他達拉非(Tadalafil)的人群中,腫瘤細胞減少,癌症細胞增多。


邁阿密大學和約翰霍普金斯大學的研究


Weed及其同事進行的研究特別針對骨髓來源的抑制細胞和調節性T細胞以及它們如何影響頭頸部鱗狀細胞癌。研究人員設計了一項雙盲,隨機,三組研究,對這類癌症患者進行手術切除腫瘤。患者在手術前每日接受10mg他達拉非(Tadalafil),每日20mg或安慰劑至少20天。

犀利士官網:https://www.cialiusa.tw/

在治療前後評估骨髓來源的抑制細胞和調節性T細胞的活性。他達拉非(Tadalafil)治療顯著降低了血液和腫瘤中兩種細胞的濃度。此外,治療後腫瘤抗原的濃度顯著增加。藥物耐受性良好,副作用最小。藥物的活性在中間劑量而不是較高劑量時達到最高。他達拉非(Tadalafil)似乎在頭頸部鱗狀細胞癌患者中以有益的方式調節腫瘤環境。

早期對他達拉非(Tadalafil)和癌症的研究

犀利士官網:https://www.cialiusa.tw/

這不是邁阿密大學科學家首次研究治療癌症的勃起功能障礙藥物。十年前,當時在約翰霍普金斯Kimmel癌症中心的Paolo Serafini博士發現,在植入結腸和乳腺腫瘤的小鼠中,犀利士的活性成分他達拉非(Tadalafil)顯著降低了腫瘤的大小。


除了男性患者強壯勃起的明顯潛在副作用外,他達拉非(Tadalafil)幾乎沒有副作用,通常被認為是非常安全的。理想情況下,參與者不知道他們是否接受他達拉非(Tadalafil)或安慰劑,但顯然許多男性患者可能會因為副作用或缺乏副作用而不敢輕易嘗試。


結論


當犀利士首次被引入時,它開始了關於勃起功能障礙的全國性對話,但我們幾乎不知道被稱為PDE-5抑制劑的那類藥物會對如此多的身體系統產生影響。對於患有勃起功能障礙的男性,犀利士,威而剛和類似的藥物可以顯著提高生活質量。隨著對這些藥物的新潛在應用的探索,那些將其用於勃起問題的男性可以放心,已經很好的安全性狀況一直在積累更多的數據。PDE-5抑制劑最終會改變性行為以外的生活,因為它們會發現更多的新用途。

犀利士官網:https://www.cialiusa.tw/

▲Mater Yenlung Chiu said that during "Cold Dew" term, there are 6 zodiac signs whose luck is too strong to catch. (Photo saurce: Pixabay)

Welcome "Cold Dew" on Sunday: Numerologist: 6 zodiac signs take positive actions 

By Master Chiu Yanlong

The cold dew officially entered on October 8th (Sunday). With the arrival of waves of northeast monsoon, the atmosphere of autumn is stronger and you can feel the coolness in the morning and evening. Chiu Yenlung, an international star numerology and Feng Shui expert, analyzed that during this solar term, special attention should be paid to driving safety, but there are 6 zodiac signs whose luck is too strong to catch. As long as they act proactively, those born in the Year of the Pig will have a chance to be promoted, and those born in the Year of the Rat will have a prosperous career. Those born under the zodiac of Rabbit will have their dreams come true, while those born under the zodiac of Ox will have their fame greatly increased. 

Master Chiu Yenlung analyzed that in this solar term (10/8-10/24), the six zodiac signs have the strongest luck, which are: 

Top 6: Monkey 

Monkey friends will have the opportunity to make a fortune during this period, and they will receive special care from the government, bosses or fans. If you market yourself well and use your communication skills to express yourself, success will be closer and closer, but no matter how busy you are, you should take good care of your health. 

Top 5: Sheep 

Friends who belong to the Year of the Sheep, during this period, you can improve your popularity and interpersonal relationships, and coupled with your hard work, you will have good harvests. It is recommended that you go to other places, overseas, the Internet, the media, higher education, religious groups, etc. If you start in the right direction, it will be easier to succeed. 

Top 4: Ox 

Friends who were born in the Year of the Ox will exude a strong sense of domineering during this period, and their reputation will greatly increase in front of friends. If you market yourself more and communicate more, you will have the opportunity to get closer to your career and real wealth. You will find that customers, partners or partners People are working hard during this period, so wait for the good news. 

Top 3: Rabbit 

Friends who were born in the Year of the Rabbit can be said to be a warrior during this period. They will become more and more popular, and the connections they have accumulated in the past will be brought closer and put to use. They will also have very strong financial luck, and all their wishes will come true. As long as you speak well, you will succeed easily.  

Top 2: Rat 

Friends who belong to the Year of the Rat, during this period, as long as you follow your own progress and plans, you will have good fortune, partial wealth, and career luck. Don't have too many doubts and tensions. Market yourself or your items to achieve success. Once it's in place, everything will be fine. 

Top 1: Pig 

Friends who were born in the Year of the Pig, although there will be a bit of pressure at work during this period, which may lead to temporary imbalances and shocks in your mood, in fact, your good reputation has spread far and wide, your eloquence and marketing skills will be improved, and you will have great fortune and fortune. When you get a chance to get promoted, you must believe in yourself, and the future will definitely be better. 

▲Master Chiu Yanlong, an international expert in feng shui and numerology.(File Photo)

 

★ 三立新聞網提醒您:

以上言論及圖片僅供參考,不代表本台立場。

犀利士

本文引用自: https://www.setn.com/News.aspx?NewsID=1364462
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